EURANASIA: Prison of Lust is an adult visual novel game about a young man (the player) who lives in a country called Euranasia. In Euranasia, the male population is rapidly declining due to the deadly 'Andras Disease', leading to a severe gender imbalance and systemic discrimination against men by the Euranasian government. You take on the role of a protagonist who becomes a rebel to fight against the unfair Euranasia government's. As a member of the resistance, you fight alongside your comrades to bring justice to the oppressed male populace. However, your action takes a dark turn when you're captured by the government's forces and thrown into the 'Prison of Lust'.

Inside the prison, you'll find yourself surrounded by a multitude of women, being the sole man among them. Both the prison guards and the inmates are exclusively female. Your mission is clear: locate 'Captain Dragon', a fellow inmate who holds vital information about the government's secrets, and find 'Oshi', a rebellious informant disguised as a prison guard. Along the way, you must secure a sword scabbard that requested by a mysterious man. To do so, the protagonist must get close to everyone inside the 'Prison of Lust' to gather the necessary information...